College of Pharmacy
 
 
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College of Pharmacy was newly established on August 1, 1999. Currently, it comprises three outstanding units with teaching, research and service functions, i.e., School of Pharmacy, Graduate Institute of Pharmaceutical Sciences and Graduate Institute of Natural Products. The main vision of this college is to provide highly competent professional pharmacists and innovative research scientists for serving and solving real human demand/problem of pharmaceutical basis. A brief introduction of the school and graduate institutes of the college is described as follows.
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School of Pharmacy and Graduate Institute of Pharmaceutical Sciences

FEATURES:

The School of Pharmacy was established on August 1, 1957. It was the first private School of Pharmacy in Republic of China. The Graduate Institute of Pharmaceutical Sciences (GIPS) was established on August 1, 1982, with a Master degree program in pharmaceutical research. A PhD program, begun on August 1, 1988, was initiated to give students an opportunity to conduct advanced research in pharmaceutical sciences. The School of Pharmacy is affiliated with a teaching hospital accredited as a first-class medical center by the Ministry of Education and the Department of Health of the Executive Yuan. Students get practical, hands-on trainings and experiences through their exposure to the hospital's pharmacy.
 
EQUIPMENT :
1.

Space : the School of Pharmacy is located in a two-story building with up-to-date facilities and well-lit, air-conditioned classrooms and laboratories. The space was designed to house 10 different compartments for pharmaceutics, medicinal chemistry, natural products, pharmaceutical and toxicological analysis, pharmacy practice and offices for faculties.

2.

Teaching and research equipment : important instruments include Nuclear Magnetic Resonance instruments (NMR-400 and NMR-200), Gas Chromatographic Mass Spectrometer (GC-MS), High-Performance Liquid Chromatograph (HPLC), Gas Chromatograph (GC), Capillary Electrophoresis System (CE), Medium Pressure Liquid Chromatograph (MPLC), Thin Layer Chromatographic (TLC) Scanner, Droplet Counter Current Chromatograph (DCCC), Spectrophotometers (UV, VIS, IR, Fluorescence), Digital Polarimeter, FTIR/Microscopy/Micro Dsc Particle Analyzer …..etc.

 
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::GRADUATE PROGRAMS IN THE PHARMACEUTICAL SCIENCES::
 
The Graduate Institute of Pharmaceutical Sciences (GIPS) offers graduate courses which lead to the degrees of Master of Science and Doctor of Philosophy. Instruction emphasizes research and is given by means of lectures, recitations and seminars combined with appropriate work in the laboratories. The GIPS is organized into five groups: Pharmaceutics, Pharmaceutical Analysis, Pharmaceutical Chemistry, Clinical Pharmacy and Applied Chemistry.
 
TEACHING PLANS :
Although the traditional lecture format is still employed in some course, a significant portion of the curriculum focuses on the acquisition of skills through the use of problem-based, students-centred learning. The program is designed to develop potentials of those who have the ability to engage in a wide range of advanced clinical pharmacy activities including advanced therapeutic services, patient consultation and clinical research. It has the following purposes: to preserve, augment, criticize and transmit pharmaceutical knowledge; to advance and generate pharmaceutical knowledge; to aid in conserving or improving the health and welfare of the public through influencing the patient, the health practitioner, or their common environment. Teaching is conducted through a mixture of lectures, practical classes, workshops, problem classes and small group tutorials.
 
COURSE CONTENTS :
The school offers a number of professional, undergraduate, and graduate programs directed at several areas of the pharmaceutical sciences. The degrees in pharmacy from Kaohsiung Medical University prepare students for careers in industry, research, hospital or community pharmacy. Our graduates are to be found in senior positions throughout the pharmacy world in all branches of the profession. The B.S. in Pharmacy Degree is a four-year curriculum composed of two years of prepharmacy general knowledge and basic science courses, followed by two years of professional coursework. This four-year program leading to a Bachelor of Science degree in Pharmacy requires the completion of a minimum of 148 credits .
 
COURSE MODULES
 
First Academic Year
Chinese Literature-4, English Reading-4, English Listening and Speaking Practice-2, General Chemistry (Including Laboratory)-4, General Biology-4, Calculus-4, Organic Chemistry-2, Pharmaceutical Botany-3, Pharmaceutical Botany Laboratory-1, Analytical Chemistry-3, Analytical Chemistry Laboratory Orientation in pharmacy-1, Physical Education, Military Training, Introduction to Computer (Including Laboratory)-2.
 
Second Academic Year
Constitution and Government-2, General physics-3, General Physics Laboratory-1, Basic Concept of Chinese Drug-1, History of Taiwan-2, Physical Pharmacy-3, Biochemistry(I)-2, Organic Chemistry-4, Organic Chemistry Laboratory-2, Physiology-4, Physiology Laboratory-1, Anatomy (including Histology)-2, Biostatics-2, Physical Education, Pharmaceutics(I)-2, Pharmacognosy(I)-1, Pharmaceutical Chemistry (I) –1, Pathology-2
 
Third Academic Year
Pharmaceutics (II)-2, Pharmaceutics Laboratory-2, Pharmacognosy(II)-2, Pharmacognosy Laboratory-2, Pharmaceutical Chemistry(II)-4, Pharmaceutical Chemistry Laboratory-2, Biochemistry(II)-2, Pharmacology-4, Pharmacology Laboratory-2, Biopharmaceutics-3, Clinical Pharmacy & Therapeutics(I)-2, Pharmaceutical Analysis(I)-2, Dispensing Pharmacy(I)-2, Physical Education Microbiology & Immunology-3, Microbiology & Immunology Laboratory-1.
 
Fourth Academic Year
Clinical Pharmacy & Therapeutics(II)-3, Pharmaceutical Analysis(II)-2, Pharmaceutical Analysis Laboratory-2, Toxicology-2, Nonprescribed Drugs-2, Dispensing Pharmacy(II)-1, Dispensing Pharmacy Laboratory-1, Clinical Pharmacokinetics-2, Pharmacy Practice (Minimum of 2 months) Human communication–2, Hospital Pharmacy Practice-6, Pharmacy Administration and Law-2.
 
FURTHER DEVELOPMENT:
A degree in Pharmacy from Koahshiung Medical University prepares and students for careers in industry, research, hospitals or community pharmacy. Pharmacists assume a wide variety of specializations within the health care field. The majority of licensed pharmacists work in community pharmacies where they have responsibilities in medication and health care of the general community. Licensed pharmacists may also work in hospitals, in posts of research and teaching, and in the pharmaceutical industry. Whereas hospital pharmacists are primarily responsible for assuring the appropriate use of medicine by hospitalized patients, research pharmacists are generally involved in the development of new medicines and dosage forms, in the determination of how medicines alleviate disease, and in the assessment of the social and economic factors influencing the use of medicines. Like teacheres, they may be involved in the education of pharmacy students and pharmacy technicians. Industrial pharmacists may work on sales drug information, regulatory affairs, production, quality control or research within the Pharmaceutical industry. Government departments with public health concerns also employ pharmacists in analytical toxicology laboratories, as inspectors, health supplies officers or in the armed forces.
 
CONTACT FOR ENQUIRIES:
Yen-Hsia Wen, Ph.D.

Hwang-Shang Kou, Ph.D.

School of Pharmacy, Kaohshiung Medical University
Kaohshiung, Taiwan
TEL:886-7-3121101 ext.2165
FAX:886-7-3210683
Email: m745004@cc.kmu.edu.tw
School of Pharmacy, Kaohshiung Medical University,
Kaohshiung, Taiwan
TEL:886-7-3121101 ext.2223
FAX:886-7-3210683
E-mail: m785010@cc.kmu.edu.tw
 
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::Graduate Institute of Natural Products::

 

The Master of Science program of the Graduate Institute of Natural Products (GINP) was established on August 1, 1992. It was the first Graduate Institute of Natural Products in the Republic of China. The PhD. courses will start on August, 2001.

The Institute is actively engaged in research projects, operating on grants sponsored by the National Science Council, the Department of Health of the Executive Yuan, etc. The goal of this Institute is to promote advanced research in Natural Medicinal Products and the programs will emphasize the following three research areas:

 
(1) Discovery of Bioactive Traditional Medicine, Terrestrial and Marine Natural Products.
  Traditional medicine is a treasury for natural products research because they have been used clinically for thousands of years. Located in the subtropics and surrounded by the ocean, Taiwan has abundant terrestrial and marine natural products. So, if we can discover bioactivities from them with scientific methods, natural products will offer us great sources of medicines and drugs in the future. At present, GNP mainly emphasizes the development in aspects of anticancer, antiviral, antiplatelet and immunologic activities.
(2) Identification of Bioactive Constituents from Natural Products.

 

During the process of applying natural products science to modern medicines, it is necessary to isolate bioactive compounds from natural products. The identification of bioactive constituents includes the characterization of chemical structures and pharmacologic mechanisms especially on molecular level
(3) Pre-clinical and Clinical Tests of Bioactive Constituents.
  Once the chemical structures and mechanisms of action of bioactive compounds have been determined, pre-clinical toxicity trials conducted in animal and kinds of pharmacologic trials must be done before clinical tests. With the establishment of the National Institute of Health (NIH), GNP will become one of pre-clinical tests centers.
 
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::Graduate Institute of Natural Products Courses::
 
Master Courses
 

Subject (Elective)

Credits
Special Topics in Pharmacognosy (Including Lab.)(I)
4
Special Topics in Pharmacognosy (Including Lab.)(II)
4
Special Topics in Medicinal Chemistry (Including Lab.)(I)
4
Special Topics in Medicinal Chemistry (Including Lab.)(II)
4
Special Topics in Natural products Chemistry (Including Lab.)(I)
4
Special Topics in Natural products Chemistry (Including Lab.)(II)
4
Special Topics in Herbology (Including Lab.)(I)
4
Special Topics in Herbology (Including Lab.)(II)
4
Special Topics in Pharmaceutical Technology (Including Lab.)(I)
4

Special Topics in Pharmaceutical Technology (Including Lab.)(II)

4
Special Topics in Biochemistry
4
Special Topics in Pharmacology
4
Special Topics in Biostatistics
4
Isolation Technique
4
Instrumental Analysis
4

Special Topics in Bioorganic Chemistry

4
Special Topics in Immunology
4
Note: In addition to thesis for master degree (6 credits), each student must complete 24 credits (including 16 elective credits).
 
 
Graduate Institute of Natural Products

Director: Yang-Chang Wu, Ph.D., Professor

Tel :(07)3121101 ext 2197
Fax:(07)3114773
Email address: yachwu@cc.kmu.edu.tw
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::Graduate Institute of Natural Products::
 

The Master of Science Program of Graduate Institute of Natural Products (GINP) was established on August 1, 1992. It was the first Graduate Institute of Natural Medicinal Products in the Republic of China. The Institute is actively engaged in research projects, operating on grants sponsored by National Science Council, the Department of Health of Executive Yuan, etc. The goal of this Institute is to promote advanced research on Natural Medicinal Products.

The Institute possesses ten specialized research departments, including 1 Pharmacognosy, 1 Pharmaceutic Botany, 1 Chinese Materia Medica, 2 Organic Chemistry, 1 Bioorganic chemistry, 2 Pharmacology and 1 Pharmaceutic Technology. Each department provides research space for graduate students and faculty. Laboratory space is usually assigned to students in conjunction with their research advisors. Among the specialized facilities available for research are:

*Suites of rooms dedicated to Natural Medicinal Products structural analysis research, including 1 Varian 400 MHz NMR, 2 Varian 200 MHz NMR, 1HP-5989 A GC/MS spectrometer and 1 Heraeus CHN-O Rapid elementary analysis instrument.

*Special laboratory for Cell Culture research, including 2 laminar flow sets, 1 CO 2

incubator, 2 freezed-dry instrument, 2 -70 ℃ refrigerators, etc.

*Other important instruments include 2 FT infrared ray instruments (FTIR), 10 high performance liquid chromatographies (HPLC), 1 medium pressure liquid chromatography (MPLC), 1 TLC scanner, 35 rotatory evaporators, 15 fraction collectors, 30 personal computers, 2 ultraviolet/ visible instrument, 1 drops counter current chromatography (DCCC), and 1 high speed counter current chromatography (HSCCC).

 

Research: MSc

The Institute welcomes applications from graduates in pharmacy and those whose initial trainings have been in other related disciplines. The MSc program requires 24 academic semester hours of accepted graduated credits (including 16 elective credits ) in addition to these for Master Degree (6 credits). A systematic procedure for monitoring MSc Degree has been developed which includes qualifying presentations, graduation presentations (at least 3 professor advisors agreeing for the pass of graduation thesis). Training in specialist skills and techniques are provided as appropriate to each student's needs. In addition to direct supervision, many international symposiums and training opportunities are available both within GINP and more general within the KMU. The Graduate Institute at Natural Products has 11 staffs (including 7 professors, 3 associate professors and 1 assistant professor, all of them possess PhD degrees) and around 25 research students. The major goal of our master program is to integrate students academic and research activities, and emphasize the acquisition of specific knowledge in Natural Medicinal Products.

 
Area of research

Identification and Discovery of Bioactive Constituents from Traditional Medicine, Terrestrial and Marine Natural Products.

 

Prof. and Director Y.C.Wu,

Prof.C.C.Lin,
Prof.I.L.Tsai,
Associ.Prof.M.H.Yen
Assist.Prof.F.R.Chang.
Prof. C.N.Lin,
 

Traditional medicines is a treasury for natural products research because they have been used clinically for thousands of years. Located in the subtropics and surrounded by the ocean, Taiwan has aboundant terrestrial and marine natural products. So, if we can discover bioactive compounds from them with scientific methods, natural products will offer us great sources of medicines and drugs in the future. At present, GINP mainly emphasizes the identification of new bioactive constituents with modern analytic methods and the development in aspects of their anticancer, antiviral, antiplatelet and immunologic activities.

Organic synthesis and Biochemical Study Natural Medicinal Products
 

Prof.L.C.Chen,

Prof.M.J.Wu,
Associ.Prof.J.J.Wang
 

Natural medicinal products are always rare and possess high economic value. After the discovery of bioactive compounds or new leaddrugs, the yield of them will become an important problem. Moreover, the structures of natural medicinal products are usually novel and interesting, the relationship of biosynthesis needs to be solved. Using modern synthesis technology, synthesis or semi-synthesis of natural medicinal products are studied. The biochemical and molecular modeling topics are also investigated.

 

Pre-clinical and Clinical Test of Bioactive Constituents

Prof.I.J.Chen,
Associ.Prof.H.F.Chiu
Associ.Prof.C.C.Wu
 

Once the chemical structures and mechanisms of action of bioactive compounds have been determined, pre-clinical toxicity trials conducted in animals and kinds of pharmacological trials must be done before clinical tests. With the establishment of the National Institute of Health (HIH), GINP will become one of pre-clinical test centers.

 

Taught courses: MSc

MSc in Natural Medicinal Products. This Course begins un September and runs for a months (24 months part-time).

Applicant should have a Graduate Certificate in Pharmacy or another related discipline in a Medicinal College or University.
This Institute has excellent teaching staff and high quality research. We hope that this outline introduction has provided you with a better idea of the opportunities available in our graduate program.